Myasthenia Gravis: Symptoms & Signs

Medically Reviewed on9/10/2019

Myasthenia gravisis an autoimmune disease affecting nerve and muscle signaling.

Signs and symptoms of myasthenia gravis include problems with vision such asdouble vision, eye muscleweakness, drooping of the uppereyelid, weakness of the arms and legs,difficulty swallowing, difficulty speaking,fatigue, andshortness of breath. Other associated symptoms can include neck weakness, changes in facial expressions, and problems withwalking(gait disturbances). Muscle weakness typically increases during activity and improves with periods of rest.

Causes of myasthenia gravis

A mistaken immune response to the nicotinic acetylcholine receptors, which are found in junctions between muscles and the nervous system, causes myasthenia gravis. In myasthenia gravis, the body produces antibodies that attack these receptors, preventing signals from reaching the muscles.

Other myasthenia gravis symptoms and signs

  • Changes in Facial Expressions
  • Difficulty Speaking
  • Difficulty Swallowing
  • Double Vision
  • Drooping of the Upper Eyelid
  • Eye Muscle Weakness
  • Fatigue
  • 我们的肌肉akness That Increases During Activity
  • Neck Weakness
  • Problems With Walking
  • Shortness of Breath
  • Weakness of the Arms and Legs

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References
Kasper, D.L., et al., eds.Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.
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