penicillin G benzathine (Bicillin L-A)

PenicillinG benzathine (Bicillin L-A) is a penicillin antibiotic that is given by deep intramuscular injection. Penicillin G benzathine kills susceptible bacteria by inhibiting the synthesis or formation of bacterial cell wall. It is thought to preferentially bind to specific penicillin-binding proteins (PBPs) found inside the bacterial cell wall. The end result of the inhibition of bacterial cell synthesis is cell lysis and the death of the susceptible bacteria.

Penicillin G benzathine has poor solubility and is therefore very slowly released from the site of injection. In the blood, penicillin G benzathine is broken down to penicillin G. Penicillin G benzathine formulation is released and absorbed slowly to allow for a more prolonged duration of action (drug works slowly over an longer period of time).

品牌可用于青霉素g是什么nzathine?

Bicillin L-A

Is penicillin g benzathine available as a generic drug?

Not available in the US

Do I need a prescription for penicillin g benzathine?

Yes

Side effects associated with penicillin G benzathine treatment are:

• hypersensitivity orallergicreactions,
• upset stomach,
• neuropathy,
• cardiac orheartproblems,
• dizziness,
• fatigue,
• headache,
• nervousness,
• pain,
• seizures,
• weakness,
• sexual dysfunction,
• 注射部位反应,
• blurred vision,
• kidney problems, and
• others.

• Streptococcal (Group A) upper respiratory infectionsAdult patients are administered a single injection of 1,200,000 units; older pediatric patients are administered a single injection of 900,000 units; infants and pediatric patients < 60 Ibs are administered 300,000 to 600,00 units.
• SyphilisFor the treatment of primary, secondary, and latentsyphilisthe recommended dose is 2,400,000 units as a one-time dose. For the treatment of tertiary and neurosyphilis the recommended dose is 2,400,000 every 7 days for a total of three doses. For the treatment of congenital syphilis in patients under the age of 2, the recommended dose is 50,000 units/kg.
• Yaws, Bejel, and Pinta The recommended dose is 1,200,000 units administered as a single injection.
• Preventionofrheumatic feverand glomerulonephritis After an acute attack, penicillin G benzathine may be given in doses of 1,200,000 units once a month or 600,000 units every 2 weeks.