Introduction to Progressive Supranuclear Palsy

Progressive supranuclear palsy, or PSP, is a rare neurodegenerative disease that is often misdiagnosed asParkinson's疾病,因为它携带similar symptoms. Because of its rarity, PSP is mostly unknown by the general public.

What Causes PSP?

PSP develops because of the deterioration of brain cells in a few small, but very important areas at the base of the brain. The most important affected area is the substantia nigra. When this area of the brain is affected by the disease, a lot of the palsy's symptoms become more visible. Research is still being conducted as to why the brain cells degenerate.

What Are the Early Symptoms of PSP?

The beginning stages of PSP include the inability to walk, falling spells, andstiffness. Falls experienced by a PSP patient are often described as having a state ofdizziness, prior to actually falling. Thisdizzinessdescription is sometimes misdiagnosed as an inner ear problem or ahardening of the arteriesthat are blocking blood flow to the brain.

Other common symptoms of PSP include:

  • Forgetfulness
  • Change in personality
  • Loss of interest in usual socializing with family and friends

What Are Some of the Later Symptoms of PSP?

The word "progressive" was included in the palsy's name because symptoms typically progressively worsen for a patient. After seven to nine years, PSP becomes more difficult to deal with. The disease usually causes physical imbalance and stiffness of the body to grow worse, makingwalkingvery difficult or sometimes impossible.

Problems with eyesight also occur in the later stages of PSP. Usually visual problems can become as much of an issue as impaired walking for the patient. Eyesight is most affected by the difficulty to aim the eye properly, making reading very hard. Another eyesight problem that is sometimes encountered is the inability to maintain visual contact with another person during conversation. PSP can also cause "tunnel vision", which sometimes causes problems while a person is trying to drive a car.

Does PSP Affect a Person Mentally?

Most PSP patients eventually experience a mild to moderate degree of mental problems. With PSP,dementia, or mentalconfusion, causes a person to have a slowed thinking process or difficulty synthesizing ideas. The slowing of thoughts and thinking makes it hard for the person to hold a conversation with others or to analyze problems.

How Is PSP Treated?

There is a range of medication that can help curb PSP's symptoms.

Sinemetis sometimes used because it contains levodopa, which aids in controlling shakiness andtremors.

Antidepressantsare often suggested by doctors, along with sleeping pills, to help PSP patients who are experiencingsleep problems. Manydrugsbeing developed to treat other neurological disorders are also being utilized to help treat PSP.

Is There a Cure for PSP?

There is no cure for PSP. Attention for a doctor and family of a PSP patient should be focused on keeping the person comfortable and creating the best quality of life possible.

WebMD Medical Reference

SLIDESHOW

Nerve Pain: Symptoms, Causes, and Treatment OptionsSee Slideshow

Health SolutionsFrom Our Sponsors

References
SOURCES:

Reviewed by Jon Glass on March 15, 2010

Baidu
map