hydrocortisone and pramoxine

• Pramoxine-hydrocortisone products are used to treatpainand inflammation caused by variousskin conditions. Hydrocortisone is a synthetic (man-made)corticosteroidthat is used on the skin (topically). The naturally-occurring corticosteroid is cortisol or hydrocortisone produced by the adrenal gland.Corticosteroidshave potent anti-inflammatory actions and also suppress the immune response.
• Pramoxine is a local anesthetic (numbing agent) that provides relief fromitchingandpain. Local anesthetics are chemicals that interfere with the function of the nerves that sense pain. Pramoxine may be used in persons who areallergicto other local anesthetics such aslidocaine, procaine, or benzocaine.
• The FDA approved hydrocortisone/pramoxine in August 1976.
• Epifoam, Pramosone, Proctofoam HC, Procort,AnalpramHC are the brand names for pramoxine-hydrocortisone products.
• Pramoxine-hydrocortisone is not available in generic form.
• You need a prescription for pramoxine-hydrocortisone.

Common side effects include:

• Burning
• Itching
• Irritation
• Dryness
• Folliculitis

Hydrocortisone/pramoxine is applied to the affected area as a thin film 3 to 4 times a day depending on the severity of condition.

There are nodrug interactionslisted for topical hydrocortisone/pramoxine.

• The use of hydrocortisone/pramoxine bypregnantwomen has not been adequately evaluated.
• It is not known if hydrocortisone/pramoxine is secreted inbreast milk.

What preparations of pramoxine-hydrocortisone are available?

• 直肠气溶胶泡沫:1% / 1%
• Cream: 0.5%/1%, 1%/1%, and 2.5%/1%
• Lotion: 1%/1% and 2.5%/1%

如何should I keep pramoxine-hydrocortisone stored?

• Hydrocortisone/pramoxine cream and lotion should be stored at room temperature between 15 C and 30 C (59 F and 86 F).
• The aerosol foam is stored at room temperature, between 20 C and 25 C (68 F and 77 F).