Generic Name:fluticasone
Brand Name:Flonase, FlonaseAllergyRelief
Drug Class:Corticosteroids, Intranasal
What is fluticasone, and what is it used for?
Fluticasone is a man-madecorticosteroidused for the management of nasal symptoms of seasonal or perennial,allergicand non-allergic rhinitisin adults and children of 4 years of age and older. Safe and effective use of fluticasone has not been established for children under the age of 4.
The exact mechanism of action of fluticasone is not known; however, it stimulates glucocorticoid receptors in humans that produces a potent anti-inflammatory response. Fluticasone also works on multiple cells and mediators that are responsible for the inflammatory symptoms of allergicrhinitis(sneezing,流鼻涕, etc).
The FDA approved fluticasone in October 1994.
What are the side effects of fluticasone?
Side effects of fluticasone include:
- headache,
- sore throat,
- nosebleeds,
- nasal burning or nasal irritation,
- nausea,
- vomiting,
- asthma symptoms, or
- cough.
Some children may experience growth suppression from use of inhaled steroids.
What is the dosage for fluticasone?
- Adults: The recommended dosing is 2 sprays per nostril daily. The maximum dose is 200 mcg/day (4 sprays). Maintenance therapy is 1 spray in each nostril daily.
- Adolescents and children 4 years of age and older: the recommended dosing is 1 spray per nostril daily (total dose 100 mcg.) Patients that do not respond adequately may increase to two sprays in each nostril once a day. The maximum dose is 200 mcg/day.
Which drugs interact with fluticasone?
Ritonavir(Norvir) andketoconazole(Nizoral,Extina,Xolegel,Kuric) increase fluticasone levels in the body by delaying its metabolism (elimination). It is not clear how important this effect is.
![](https://images.medicinenet.com//images/slideshow/allergy-triggers-s1-discovery.jpg)
SLIDESHOW
Common Allergies: Symptoms and SignsSee SlideshowPregnancy and breastfeeding
- There are no adequate studies of fluticasone to determine its safety and effectiveness inpregnantwomen.
- It is not known whether fluticasone entersbreast milk; therefore, it is best to be cautious before using it innursingmothers.
What else should I know about fluticasone?
- Fluticasone propionate nasal spray is available as a 16 gm bottle, providing a total of 120 sprays. Each spray contains 50 mcg of fluticasone propionate.
- Fluticasone propionate should be store between 4 C and 30 C (39 F and 86 F).
- Brand names for fluticasone propionate are Flonase and FlonaseAllergyRelief.
- Flonase is available by prescription andover-the-counter(OTC).
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Summary
Fluticasone propionate nasal spray is a corticosteroid prescribed for the management of symptoms of seasonal or perennial allergic and non-allergic rhinitis. Side effects of fluticasone include headache, sore throat, nosebleeds, nasal burning or nasal irritation, nausea, vomiting, asthma symptoms, or cough. Consult with your doctor if pregnant or breastfeeding.
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What Is Mucus?
Mucus is a normal substance produced by lining tissues in the body. Excess mucus or mucus that is yellow, green, brown, or bloody may indicate a problem. Mucus production may increase when allergies, a cold, flu, cough, or sore throat are present. Antihistamines and cold and flu medications may help alleviate excess mucus. A neti pot may be used to decrease nasal congestion and clear mucus.
Sinus Infection (Sinusitis)
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Chronic Rhinitis and Post-Nasal Drip
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Allergy (Allergies)
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Hay Fever (Allergic Rhinitis)
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Why Won’t My Allergy Symptoms Go Away?
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What Are the Symptoms of Ragweed Allergy?
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How Do You Know if You Are Allergic to Pollen?
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Should I Exercise Outside if I Have Allergies?
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What Are Typical Allergy Symptoms?
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What Foods Cause Oral Allergy Syndrome?
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What Are Typical Seasonal Allergy Symptoms?
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Prevention & Wellness
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