timolol/dorzolamide drops - ophthalmic, Cosopt

BRAND NAME(S): Cosopt

Medication Uses|How To Use|Side Effects|Precautions|Drug Interactions|Overdose|Notes|Missed Dose|Storage

USES:This product contains twodrugsused to treat high pressure inside the eye due toglaucoma(open angle-type) or other eye diseases (e.g.,ocularhypertension). Lowering high pressure inside the eye helps to preventblindness。This medication works by decreasing the amount of fluid within the eye.Timololbelongs to a class of drugs known asbeta-blockers, anddorzolamidebelongs to a class of drugs known as carbonic anhydrase inhibitors.

HOW TO USE:Read the Patient Information Leaflet provided by your pharmacist before you start using timolol/dorzolamide and each time you get a refill. If you have any questions regarding the information, consult your doctor or pharmacist.This medication is for use in the eye(s), usually one drop in the affected eye(s) 2 times a day, or as directed by your doctor.To apply eye drops, wash your hands first. To avoid contamination, do not touch the dropper tip or let it touch your eye or any other surface.Some products contain a preservative that may be absorbed bycontact lenses。If you are using a product with a preservative and you wear contact lenses, remove the lenses before using the eye drops. Wait at least 15 minutes before putting in your contact lenses.Tilt your head back, look upward and pull down the lowereyelid袋。直接持有滴管哟ur eye and place one drop in your eye. Look downward and gently close your eyes for 1 to 2 minutes. Place one finger at the corner of your eye (near the nose) and apply gentle pressure. Try not to blink and do not rub your eye. This will prevent the medication from draining out. Repeat these steps for your other eye if so directed.Do not rinse the dropper. Replace the dropper cap after each use.If you are using another kind of eye medication (e.g., drops or ointments), wait at least 10 minutes before applying other medications. Use eye drops before eye ointments to allow the eye drops to enter the eye.Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same times each day. It is important to continue using this medication even if you feel well. Most people withglaucomaor high pressure in the eyes do not feel sick.

SIDE EFFECTS:Temporaryblurred vision, temporary burning/stinging/itching/redness of the eye,watery eyes,dry eyes, feeling as if something is in the eye, sensitivity of eyes to light, strange taste in the mouth, orheadachemay occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur:dizziness, slow/irregular heartbeat, muscleweakness, mental/情绪changes, coldness/numbness/painin the hands orfeet。Tell your doctor immediately if any of these rare but very serious side effects occur: vision changes, signs of akidney stone(e.g.,painin the back/side/abdomen,nausea/vomiting,blood in the urine), yellowing eyes or skin,dark urine, unusualtiredness/weakness,easy bruising/bleeding, signs of infection (e.g.,fever,chills, persistentsore throat).Seek immediate medical attention if any of these rare but very serious side effects occur: persistenteye rednessor discharge, eye or eyelid swelling,eye pain, troublebreathing, sudden unexplainedweight gain,chest pain, weakness on one side of the body, slurred speech,confusion, persistentdizziness,fainting。A very seriousallergic reactionto this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a seriousallergicreaction may include:rash,itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS:Before using timolol/dorzolamide, tell your doctor or pharmacist if you are allergic to these drugs; or if you have any otherallergies。本产品可能含有活性成分(such as preservatives like benzalkonium chloride), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: lung disease (e.g., current or past history ofasthma, severechronic obstructive pulmonary disease), certain types of irregular heartbeats (e.g., sinus bradycardia, second or third degree AV block), certain types ofheart disease(e.g., severeheart failure).Before using this medication, tell your doctor or pharmacist your medical history, especially of:kidney disease,kidney stones,liver disease,diabetes, overactivethyroid disease, muscle weakness disorders, low blood flow to the brain (cerebrovascular insufficiency), severeallergies。If you develop an eye infection or injury, or have eye surgery, check with your doctor about whether you should continue to use your current bottle of timolol/dorzolamide. You may be advised to start using a new bottle.Before having surgery, tell your doctor or dentist that you are using this medication.If you havediabetes, this product may prevent the fast/pounding heartbeat you would usually feel when your bloodsugarlevel falls too low (hypoglycemia). Other symptoms of低血糖, such as dizziness andsweating, are unaffected by this drug.This drug may cause temporary blurred vision. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.This medication should be used only when clearly needed duringpregnancy。Discuss the risks and benefits with your doctor.This drug passes intobreast milk。Consult your doctor before breast-feeding.

DRUG INTERACTIONS:Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: high doses ofaspirinor related salicylates, oral beta-blockers (e.g.,propranolol),calcium channel blockers(e.g.,diltiazem,verapamil), oral carbonic anhydrase inhibitors (e.g.,acetazolamide,methazolamide),clonidine, certainantidepressants(e.g., SSRIs such asfluoxetine),digoxin, epinephrine,fingolimod,methyldopa,奎尼丁, reserpine,theophylline。Low-dose aspirin, as prescribed by your doctor for specific medical reasons such asheart attackorstroke prevention(usually these dosages are 81-325 milligrams per day), should be continued. Consult your doctor or pharmacist for more details.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

QUESTION

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OVERDOSE:This medicine may be harmful if swallowed. If swallowing or overdose is suspected, contact apoison controlcenter or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: trouble breathing or slow/irregular heartbeat.

NOTES:Do not share this medication with others.Laboratory and/or medical tests (e.g., eye exams) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

MISSED DOSE:If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE:Store at room temperature away from light and moisture. Do not store in the bathroom. Store the single-use containers in the pouch. Discard any unused single-use containers 15 days after opening the pouch. Keep all medications away from children and pets.This product is normally colorless. Discard the solution if it changes color, becomes cloudy, or develops particles.If you are using the single-use containers, discard any unused medication immediately after each use.Do notflushmedications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Information last revised February 2014. Copyright(c) 2014 First Databank, Inc.