![Ankylosing spondylitis is a type of arthritis that largely affects the joints and ligaments in your spine. Magnetic resonance imaging (MRI) is one of the earliest ways to detect and diagnose ankylosing spondylitis (AS).](https://images.medicinenet.com/images/article/main_image/doctor-review-spine-hip-scan-image-computer.jpg?resize=650px:*&output-quality=75)
Magnetic resonance imaging(MRI) is one of the earliest ways to detect and diagnoseankylosing spondylitis(AS). An early diagnosis can help prevent later structural changes to your spine that could severely impair your body’s ability to function.
MRI has even helped advance our understanding of AS. It has helped researchers pinpoint regions where ligaments attach to bones — called entheses — as areas where inflammatory cells can invade and potentially alter your bone marrow.
What is ankylosing spondylitis?
Ankylosing spondylitisis a type ofarthritisthat largely affects the joints and ligaments in your spine.
In some cases, the vertebrae in your lower spine will fuse, causing severestiffnessandpain. Other people will experience only occasional episodes of mildback pain. In either case, there’s no cure.
AS can affect other joints, including those in your:
- Pelvis
- Ribs
- Shoulders
- Knees
- Ankles
- Heels
Who gets ankylosing spondylitis?
In around 80% of cases, you’ll start to feel AS symptoms before 30. Only 5% of patients are over 45. The condition is also twice as common in men than women.
There’s also one genetic link to AS: a gene called HLA-B27. If you have a family history of AS, you likely have this gene, and your doctor may order a blood test to confirm.
HLA-B27基因的人倾向于开发disease around 25 years of age, while those without it show symptoms closer to 28. It’s important to keep in mind that not everyone with HLA-B27 will develop AS.
What are the symptoms of ankylosing spondylitis?
The main symptom of AS islower back paincaused by inflammation. Still, there are other symptoms that you may experience:
- Fatigue
- Loss of appetite
- Weight loss
- Skinrashes
- Abdominal pain
- Loose bowel movements
If you have AS, there’s a good chance you have other conditions or symptoms that will help your doctor pinpoint this difficult-to-diagnose condition. These include:
- Psoriasis:Theitchyskin disease found in around 9% of people with AS
- Iritis:The sudden appearance of眼睛的问题likepain, redness, and light sensitivity found in 20% to 40% of all AS cases
- Crohn’s disease andulcerative colitis:Irritable bowelconditions found in about 6% of people with AS.
People who have one or more of these conditions and AS tend to have worse symptoms overall. We need more research to understand why these specific conditions are connected to AS.
One hint is thatIritis, Crohn’s disease, andulcerative colitisalso involve inflammation. This is a possible link to the inflammatoryback painof AS.
The condition tends to cause lethargy and can often get in the way of your everyday life. The pain and loss of flexibility can make it difficult for people to continue their jobs and maintain theirmental health.
If you have AS, it’s important to seek the help you need when you need it, including therapy and counseling services.
Is an MRI better than X-rays for diagnosing ankylosing spondylitis?
A formal diagnosis of ankylosing spondylitis used to require evidence of severe changes to your sacroiliac joints throughX-rays. These joints act asshockabsorbers for your spine and transfer force from your lower body into your upper body. The problem is this damage can take up to ten years to become visible, leading to seven to 10 years of delayed diagnosis.
MRIsuse powerful magnets to create images of each section of a body part, such as a joint. A computer then combines these slices to create a three-dimensional model.
An MRI can help your doctor detect inflammation in your lower (axial) spine and your sacroiliac joints. MRI-confirmed inflammation in these regions, combined with other risk factors and symptoms, is a good indication you have ankylosing spondylitis.
An MRI can detect symptomatic inflammatory changes many years earlier than X-rays. It’s by far the better imaging method for your earliest possible diagnosis. Computed tomography (CT) scans are also much better than X-rays at detecting these early signs of inflammation.
What are other ways to diagnose ankylosing spondylitis?
Another essential part of diagnosing AS is a detailed physical exam. This will include an inspection of your joints and flexibility. You may also be asked to breathe deeply to check for any stiffness or inflammation in your ribs.
Since persistentlower back painis the most common symptom, your doctor will want to know specific details to determine if it’s caused by inflammation or mechanical problems. The pain needs to continue for at least three months before this disease is considered a possibility.
Unlike mechanical causes, inflammatory ASback paintends to be:
- Worse when you first wake up
- Worse when you sit still for a long time
- Better when you stretch andexercise
- So severe in the second half of the night that the pain can wake you up
- Accompanied by alternating pain in your left and right buttocks
You can help your doctor with this diagnosis by keeping careful track of yourback paindetails.
![](https://images.medicinenet.com//images/slideshow/rheumatoid_arthritis_s1_what_is_ra.jpg)
SLIDESHOW
What Is Rheumatoid Arthritis (RA)? Symptoms, Treatment, DiagnosisSee SlideshowWhat are treatment options for ankylosing spondylitis?
Treatment for this disease focuses on relieving your symptoms and slowing the damage caused by AS. The three main treatment techniques include:
- Medications:The most commonly recommended medication isover-the-counteranti-inflammatories, likeibuprofen.Corticosteroidscan be directly injected into problematic joints, and newer biological medications can interfere with your immune system’s inflammation response.
- Physical Therapy:Essential for correcting your posture — both while awake and asleep — and figuring out the most appropriateexerciseregime for your body.
- Surgery:Used to repair severe joint damage caused by the disease but must be considered on a case-by-case basis.
When should you see a doctor?
Part of the difficulty with catching ankylosing spondylitis early is that few young people seek medical attention for back pain. Regardless of your age, you should seek medical help if your back pain lasts for more than three months or if you believe it’s caused by persistent inflammation.
一个早期诊断可以帮助防止一些长期effects, so it’s better to see your doctor as soon as you notice problematic symptoms.
Health News
- Could Hair Relaxers Affect a Woman's Fertility?
- Lymph Node Removal During Breast Cancer Mastectomy: Is It Overdone?
- Opioid Addiction Treatment Rates in U.S. Have Flatlined, Study Finds
- Many American Teens Are in Mental Health Crisis: Report
- Why People Love Selfies: It's Not About Vanity
More Health News »
Health SolutionsFrom Our Sponsors
Johns Hopkins Arthritis Center: "Ankylosing Spondylitis."
National Institutes of Health: "Ankylosing Spondylitis."
Stanford Healthcare: "Diagnosis."
The Journal of the Canadian Chiropractic Association: "Ankylosing spondylitis: recent breakthroughs in diagnosis and treatment."
Wong, M., Sinkler, M.A., Kiel, J. StatPearls: "Anatomy, Abdomen, and Pelvis, Sacroiliac Joint." StatPearls Publishing, 2021
Top Will Ankylosing Spondylitis Show Up on an MRI Related Articles
Ankylosing Spondylitis
Ankylosing spondylitis is a type of arthritis that causes chronic inflammation of the spine. The tendency to develop ankylosing spondylitis is genetically inherited. Treatment incorporates medications, physical therapy, and exercise.Ankylosing Spondylitis Quiz
What is ankylosing spondylitis? Take this quiz to learn the causes, symptoms, and treatments for this painful disorder.Ankylosing Spondylitis: Symptoms, Diagnosis, and Treatment
What is ankylosing spondylitis (AS)? Ankylosing spondylitis is arthritis of the spine. Learn diet and exercise tips for AS, and how to improve posture. See the diagnosis steps for AS, and find helpful treatments that relieve pain and stiffness.Best Exercises for Ankylosing Spondylitis
See pictures of how to do exercise moves that will help with back strength and flexibility when you have ankylosing spondylitis of the spine.What Is the Best Medication for Ankylosing Spondylitis (AS)?
Ankylosing spondylitis treatment typically includes the use of nonsteroidal anti-inflammatory drugs (NSAIDs) that can help relieve inflammation, pain and stiffness. Other treatment options may include TNFa blockers and IL-17 inhibitors for patients with persistently high symptoms.Can Surgery Help Ankylosing Spondylitis (AS)?
Ankylosing spondylitis is a type of arthritis that affects the spine and large joints. Surgery can help people with ankylosing spondylitis if they are in severe pain, experience severely limited mobility or have significantly reduced quality of life.Can You Get Disability for Ankylosing Spondylitis?
A patient is eligible for disability benefits for ankylosing spondylitis (AS) if the condition is considered severe and serious. Below are the criteria to get disability benefits for ASHow Do You Determine if You Have Ankylosing Spondylitis?
Ankylosing spondylitis is a form of arthritis that targets the spine. You determine if you have ankylosing spondylitis by undergoing a medical exam, imaging tests, and blood tests.How Do You Permanently Cure Ankylosing Spondylitis?
There is no permanent cure for ankylosing spondylitis, but symptoms can be managed effectively with appropriate treatment, physical therapy, exercise and lifestyle modifications.Is Turmeric Good for Ankylosing Spondylitis?
Ankylosing spondylitis is an inflammatory joint condition. There is no evidence of effectiveness of turmeric in people with ankylosing spondylitis. However, it seems to work to reduce the pain and severity of signs and symptoms in people with arthritis.Rheumatoid Arthritis vs. Ankylosing Spondylitis
Learn the differences between rheumatoid arthritis and ankylosing spondylitis below.What Aggravates Ankylosing Spondylitis?
Pain management for ankylosing spondylitis requires identifying the triggers that aggravate your symptoms. Here are those possible causes of AS.What Is the Best Diet for Ankylosing Spondylitis (AS)?
Ankylosing spondylitis is a type of arthritis that affects the spine and large joints. The best diet for ankylosing spondylitis includes the Mediterranean diet or a diet rich in lean protein, vegetables and fruit that eliminates refined flour, sugar, alcohol and processed foods.什么引发强直性Spondylitis?
Ankylosing spondylitis (AS), also called Bechterew disease, is a chronic inflammatory disease. Ankylosing spondylitis affects the joints of the body, especially the small joints of the spine and the pelvic (hip) bone. It can also affect multiple organ systems in rare conditions. Prolonged inflammation of the joints eventually leads to the fusion of the joints leading to deformities.什么引发强直性Spondylitis (AS)?
Ankylosing spondylitis (AS) is an autoimmune disease that has no specific cause. While genetic factors are believed to be involved, particularly in people with a gene called HLA-B27, some people with the gene never develop the condition.